Table 1.
Laboratory Data on Admission and at Time of MAS Development.
| On admission | Complicated by MAS | Normal range | ||||
|---|---|---|---|---|---|---|
| Urinalysis | ||||||
| Protein | - | - | ||||
| Occult blood | - | - | ||||
| Blood count | ||||||
| White blood cells (/μL) | 11,970 | 20,240 | 3,300-8,800 | |||
| Neutrophil (%) | 88.2 | 97.0 | 42.0-74.0 | |||
| Hb (g/dL) | 9.6 | 9.3 | 13.5-17.0 | |||
| Plt (/μL) | 39.0 | 28.5 | 13.0-35.0 | |||
| ESR (mm/hr) | 140 | 56 | ||||
| Serum chemistry | ||||||
| BUN (mg/dL) | 13.3 | 21.9 | 8-22 | |||
| Cr (mg/dL) | 0.75 | 0.73 | 0.60-1.00 | |||
| Na (mEq/L) | 134 | 132 | 135-149 | |||
| K (mEq/L) | 4.3 | 5.1 | 3.5-4.9 | |||
| Cl (mEq/L) | 98 | 98 | 96-108 | |||
| AST (IU/L) | 41 | 1,989 | 13-33 | |||
| ALT (IU/L) | 22 | 821 | 8-42 | |||
| LDH (IU/L) | 357 | 2,643 | 119-229 | |||
| TP (g/dL) | 7.4 | 6.0 | 6.7-8.3 | |||
| Alb (g/dL) | 2.5 | 2.4 | 4.0-5.0 | |||
| TG (mg/dL) | 78 | 139 | 30-150 | |||
| Ferritin (ng/mL) | 8,412 | 34,160 | 6.9-323 | |||
| FDP-DD (μg/mL) | 6.2 | 33.8 | <1.0 | |||
| Immunological findings | ||||||
| CRP (mg/dL) | 15.7 | 2.9 | 0.0-0.3 | |||
| IgG (mg/dL) | 1,775 | 870-1,700 | ||||
| IgA (mg/dL) | 283 | 110-410 | ||||
| IgM (mg/dL) | 89.5 | 33-190 | ||||
| C3 (mg/dL) | 184.7 | 65-135 | ||||
| C4 (mg/dL) | 41.7 | 13-35 | ||||
| Anti-nuclear antibody | ×40 | - | ||||
| RF (IU/mL) | 2.0 | <20 | ||||
| MPO-ANCA | - | - | ||||
| PR3-ANCA | - | - | ||||
| sIL-2R (U/mL) | 1,490 | 2,870 | 220-530 | |||
| Cytokine | ||||||
| IL-18 (pg/mL) | 33,500 | 210,000 | <500 | |||
| IL-6 (pg/mL) | 42 | 18 | <5 | |||
| neopterin (nmol/L) | 21.8 | 113 | <5 | |||
| sTNF-R I (pg/mL) | 4,240 | 7,000 | 484-1,407 | |||
| sTNF-R II (pg/mL) | 6,900 | 46,500 | 892-2,262 | |||
| sTNF-R II/I | 1.6 | 6.6 | ||||
MAS: macrophage activation syndrome