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Splenectomy: macroscopic and pathological findings of the spleen. Splenectomy was performed after ligation of the splenic artery (a). Macroscopic findings included a massively enlarged spleen (4,300 g in weight and 28×21 cm in size) (b). A microscopic specimen of the spleen revealed non-caseating epithelioid granuloma (red arrow: multinucleated giant cells) (c) with multinucleated giant cells (d). Spleen infarction (blue arrow) was also detected in the removed spleen (e).
