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(A) Ex vivo biodistribution of unchelated 89Zr in STA mice 48 h p.i. (B) Uptake (% ID) of 89Zr-NSSL-MPS in the femur and shoulders of RA and control mice (blue dots, red squares and green triangles) and uptake (% ID) of unchelated 89Zr NSSL-MPS in the femur and shoulders of STA mice (purple diamonds). (C) Plot of % ID of 89Zr-NSSL-MPS and unchelated 89Zr versus swelling of wrists and (D) versus swelling of ankles at day 9 post serum injection. All error bars represent mean ± SD.
