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Ex vivo tumor-to-background ratio per dose cohort.
| Dose-cohort | TBR | |
|---|---|---|
| Visualization | Spectroscopy | |
| 10mg | 1.61 ± 0.93 | 2.86 ± 0.29 |
| 25mg | 2.02 ± 0.55 | 1.99 ± 1.62 |
| 50mg | 1.81 ± 0.32 | 1.48 ± 0.52 |
| 15mg* | 3.06 ± 0.43 | 2.50 ± 0.19 |
| 25mg* | 3.10 ± 2.53 | 2.81 ± 1.27 |
Median tumor-to-background ratios shown both for fluorescence visualization using a closed-field imaging device and quantification of intrinsic fluorescence values using MDSFR/SFF spectroscopy.
