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Characterization of AS1411/hemin-PA. (A) HPLC chromatogram of AS1411-PA conjugate. (B) UV-vis-NIR spectra of hemin, AS1411-PA, and AS1411/hemin-PA. (C) Oxygen generation in hydrogen peroxide solution with or without addition of AS1411/hemin-PA at room temperature. (D) Singlet oxygen generation, as determined by the increased SOSG fluorescence of AS1411-PA and AS1411/hemin-PA with or without hydrogen peroxide under 670-nm NIR light irradiation.
