Figure 3.
(A) Scheme of aptamer-based molecular domino reactor to generate 1O2. (B) Flow cytometry assay showing the binding affinities of MCF-7 cell after incubation of AS1411-0T-PA, AS1411-4T-PA, AS1411-10T-PA, AS1411-20T-PA, AS1411-40T-PA. (C) Singlet oxygen generation, as determined by the increased SOSG fluorescence, of AS1411/hemin-4T-PA, AS1411/hemin-10T-PA, AS1411/hemin-20T-PA, and AS1411/hemin-40T-PA in the presence of hydrogen peroxide under 670-nm NIR light irradiation for 10 min. P values in (C) were calculated by Tukey's post-test (***P < 0.001, **P < 0.01 or *P < 0.05).