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. 2020 Mar 4;10(9):4233–4249. doi: 10.7150/thno.40664

Figure 1.

Figure 1

Glucose intolerance and reduced insulin levels in Egr1-/- mice. A: Body weights of male mice fed RC at 2-month-old and a HF diet for 2 months starting at 2 months of age. Numbers of mice are inside bars. B: Organ weight ratios in 4-month-old male mice fed RC (upper panel) and a HF diet (lower panel) for 2 months. Gon, gonadal; Ing, inguinal WAT, white adipose tissue; BAT, brown adipose tissue. C and D: Plasma (C) glucose and (D) insulin levels during OGTT in 4-month-old male mice fed RC (upper panels) and a HF diet (lower panels) for 2 months. WT RC, n=6; Egr1-/- RC, n=11; WT HF, n=16; Egr1-/- HF, n=15. *P<0.05, **P<0.01 and ***P<0.001 compared to WT.