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. 2020 Mar 4;10(9):4233–4249. doi: 10.7150/thno.40664

Figure 6.

Figure 6

Glucagon-positive α cells expressed typical β-cell transcription factors in the islets of HF-fed Egr1-/- mice. Confocal images of co-staining for the markers of β-cell (insulin; white) and α-cell (glucagon; green) with (A) PDX1, (B) PAX4, (C) PAX6, and (D) ARX (red) in the pancreas of HF-fed Egr1-/- and WT mice. The enlarged images highlight the representative co-localization with 5× magnification from white squares in the overlay images. The fluorescence intensity profile from green, red, and white channels is shown.