Ecker 2015.
Methods | Study design: retrospective cohort study | |
Participants | Country: USA.
Number eligible: 73.
Post‐randomisation drop‐outs: 0 (0%).
Number analysed: 73.
Average age: 64 years.
Females: 16 (21.9%).
Stage I: 13(17.8%).
Stage II: 19 (26%).
Stage III: 31 (42.5%).
Stage IV: not stated
Squamous cell carcinoma: 4 (5.5%).
Adenocarcinoma: 68 (93.2%).
Study design: Retrospective cohort study with contemporary controls
Total follow‐up in months: median:10 months
ASA: not stated
Location: not stated Inclusion criteria Patients undergoing transhiatal oesophagectomy |
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Interventions | Group 1: laparoscopic transhiatal oesophagectomy (N = 36). Further details: number of ports ‐ not stated; minilaparotomy incision size ‐ not stated; drain use ‐ not stated. Group 2: open transhiatal oesophagectomy (N = 37). Further details: incision size ‐ not stated; drain use ‐ not stated. | |
Outcomes | The outcomes reported were short‐term and long‐term mortality, oesophageal stenosis, short‐term recurrence, blood transfusion, length of hospital stay, positive resection margin, and number of lymph nodes harvested. | |
Notes | Proportion of people with cancer: 96% to 99% (error in the number of patients with different aetiologies) Conversion: 4/36 (11.1%) |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Bias due to confounding | Unclear risk |
No information Comment: There was no evidence of baseline differences between the groups. However, the sample size was not sufficient to identify baseline differences. In addition, not all confounding factors were listed in the baseline differences table (for example, no information was presented on the differences in the size of the tumours) |
Bias due to selection of participants to intervention and control | Unclear risk |
No information Comment: Method of selection of participants to intervention and control was not reported. |
Bias due to differences in co‐interventions which were different between the groups | Unclear risk |
No information Comment: It was not clear there were other differences in care of the patient apart from the intervention and control. |
Bias in the measurement of outcomes | Unclear risk |
No information Comment: Information on observer blinding was not available. |
Bias due to missing data | Low risk |
Low risk of bias Comment: All patients were included in the analysis. |
Bias in selection of the reported findings | High risk |
Serious risk of bias Comment: Morbidity was not reported. |