Valenti 2008.
Methods | Study design: prospective cohort study | |
Participants | Country: UK.
Number eligible: 40.
Number excluded: 0 (0%).
Number analysed: 40.
Average age: 67 years.
Females: 8 (20%).
Stage I: not stated
Stage II: not stated
Stage III: not stated
Stage IV: not stated
Squamous cell carcinoma: 9 (22.5%).
Adenocarcinoma: 28 (70%).
Study design: Prospective cohort study with contemporary controls
Total follow‐up in months: not stated
ASA: ASA I or II: 12 versus 17; ASA III or IV: 4 versus 7
Location: lower third Inclusion criteria Patients undergoing transhiatal oesophagectomy for oesophageal cancer |
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Interventions | Group 1: laparoscopic transhiatal oesophagectomy (N = 16). Further details: number of ports ‐ 5; minilaparotomy ‐ 7 cm incision; drain use ‐ not stated. Group 2: open transhiatal oesophagectomy (N = 24). Further details: incision size ‐ not stated; drain used‐ not stated. | |
Outcomes | The outcomes reported were short‐term mortality and number of lymph nodes harvested. | |
Notes | Proportion of people with cancer: 93% (remaining patients had high grade dysplasia) Conversion: 0/16 (0%) |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Bias due to confounding | Unclear risk |
No information Comment: There was no evidence of baseline differences between the groups. However, the sample size was not sufficient to identify baseline differences. In addition, not all confounding factors were listed in the baseline differences table (for example, no information was presented on the differences in the stage of the tumours) |
Bias due to selection of participants to intervention and control | Unclear risk |
No information Comment: Method of selection of participants to intervention and control was based on surgeon's preference. |
Bias due to differences in co‐interventions which were different between the groups | Unclear risk |
No information Comment: It was not clear there were other differences in care of the patient apart from the intervention and control. |
Bias in the measurement of outcomes | High risk |
High risk of bias Quote: "No blinded assessors (author replies)". |
Bias due to missing data | Low risk |
Low risk of bias Quote: "No patients excluded from analysis (author replies)". |
Bias in selection of the reported findings | High risk |
Serious risk of bias Comment: Morbidity was not reported. |