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. 2020 Mar 6;204(7):1998–2005. doi: 10.4049/jimmunol.1901385

FIGURE 6.

FIGURE 6.

Human anti-Gal Abs were detected in the serum of NSG/α-Galnull mice following human immune reconstitution. Serum from NSG/α-Galnull mice were analyzed for production of human (A) or murine (B) anti-Gal Abs after differentiation of human CD34+ HSCs into T cells and B cells and SWBC boosting. Data are represented as mean ± SD relative to human control serum or the murine α-Gal control Ab M86 VH3 IgG.