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. 2012 Oct 17;2012(10):CD001405. doi: 10.1002/14651858.CD001405.pub3

Enzelsberger 1990 L.

Methods RCT, duration of study 4/52
Participants 35 women 
 Inclusion criteria: urgency symptoms, urgency urinary incontinence, frequency, nocturia 
 Exclusion criteria: renal disease, infections in the urogenital area, anticholinergic or hormone therapy
Interventions Group A (n=15): 0.5 or 1 mg oestriol vaginally 
 Group B (n=20): 2 mg oestriol vaginally
Outcomes Urinary diary, cystoscopy, urodynamics, urethral and vaginal smear
Notes No endometrial stimulation or breast tenderness noted
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk no description
Allocation concealment (selection bias) Unclear risk no description
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk no description
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk no description