Table 2.
The levels of oxidative stress biomarkers.
| Parameters | CG | CHG | MG | CHMG | IG | CHIG |
|---|---|---|---|---|---|---|
| U87 | ||||||
| GSH (mg/L) | 11.9 ± 1.5 | 10.1 ± 1.7∗ | 8.5±0.9∗∗ | 7.8±0.9∗∗ | 15.6±2.0∗∗∗ | 14.3±2.2∗∗ |
| CAT (mg/L) | 16.4 ± 3.1 | 14.8 ± 5.4∗ | 7.2±2.7∗∗∗ | 6.8±1.4∗∗∗ | 17.5 ± 3.2 | 16.1 ± 3.4 |
| MDA (mmol/L) | 4.9 ± 1.3 | 7.8±2.2∗∗ | 8.4±2.4∗∗ | 8.5±1.3∗∗ | 3.7±1.2∗∗ | 3.9 ± 2.0∗ |
| SOD (U/L) | 371.4 ± 62.3 | 221.5±60.7∗∗ | 202.3±80.5∗∗∗ | 200.8±34.3∗∗∗ | 491.2±69.6∗∗ | 470.5±60.1∗∗ |
| HS683 | ||||||
| GSH (mg/L) | 14.1 ± 2.3 | 11.5±1.9∗∗ | 7.5±1.4∗∗∗ | 7.9±1.2∗∗∗ | 16.3 ± 2.0∗ | 16.0 ± 2.5∗ |
| CAT (mg/L) | 15.8 ± 3.4 | 12.0 ± 3.8∗ | 7.9±3.7∗∗∗ | 6.8±1.0∗∗∗ | 18.8 ± 3.6∗ | 18.0 ± 3.1∗ |
| MDA (mmol/L) | 4.2 ± 1.4 | 8.6±2.5∗∗ | 11.7±2.1∗∗∗ | 10.6±2.3∗∗∗ | 3.5±1.1∗∗ | 3.2±1.3∗∗ |
| SOD (U/L) | 345.5 ± 59.1 | 303.7 ± 63.4∗ | 281.3±49.6∗∗ | 257.9±36.8∗∗ | 396.1 ± 69.3∗ | 390.2 ± 60.7∗ |
Note: CG—control group; CHG—chidamide group; MG—miR-338-5p mimic group; IG—miR-338-5p inhibitor group; CHMG—chidamide-treated miR-338-5p mimic group; CHIG—chidamide-treated miR-338-5p inhibitor group. N = 5 for each group and ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 vs. the CG group.