Table 6.

Logistic regression of clinical and single-nucleotide polymorphism (SNP) status variables in RSV bronchiolitis

Variable	Crude OR	CIOR	ORModel 1 (severe retractions, wheezing, antibiotics, systemic corticosteroids, bacterial coinfection)	CIOR	ORModel 2	CIOR
Infant aged <6 months*	1.99	1.37–2.89	6.02	3.36–10.8	6.02	3.35–10.79
Newborn weight >4 kg	1.2	0.63–2.29
Male sex	1.2	0.83–1.75
Female sex	1.2	0.83–1.75
Obesity	0.89	0.59–1.36
Fever*	1.55	1.07–2.25	1.84	1.13–3.03	1.85	1.13–3.03
Severe retractions	3.02	1.7–5.36	2.09	1.07–4.09	2.09	1.07–4.09
Cyanosis/apnea*	2.08	1.19–3.65
Prolonged capillary refill*	5.38	2.53–11.4	2.82	1.19–6.71	2.82	1.19–6.71
Dehydration*	6.85	1.97–23.7
Prolonged expiration	1.5	0.99–2.28
Wheezing	1.16	0.8–1.69
Antibiotics*	5.24	3.47–7.93	3.75	2.32–6.05	3.75	2.32–6.05
Systemic corticosteroids*	2.5	1.72–3.64	4.07	2.35–7.05	4.07	2.35–7.05
Opacity in chest X-ray*	2.5	1.6–4.13
Atelectasis in chest X ray*	2.29	1.46–3.62	2.88	1.67–4.99	2.89	1.67–5.0
Tobacco exposure at home*	1.82	1.26–2.64	1.72	1.1–2.69	1.72	1.1–2.69
Maternal smoking during pregnancy	0.96	0.6–1.56
Phototherapy	1.43	0.88–2.31
Breastfeeding at 6 months of age	1.07	0.7–1.63
Family history of asthma*	1.38	0.96–1.99
Clinical bacterial coinfection*	4.5	2.89–7.0
TT genotype rs12979860*	0.69	0.42–1.15
GG genotype rs8099917*	0.44	0.24–0.84	0.3	0.14–0.65	0.3	0.14–0.65

OR Model 1: stepwise forward

OR Model 2: stepwise reverse

*Significant in the univariate analysis (Table 4)