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. 2019 Feb 26;39(Suppl 1):1–151. doi: 10.1007/s10875-019-00597-5
Table 1 Study STP-2279-002: Patient Data (Six Patients)
Patient ID Gender/Age/Race b Start of Adagen Lead In Phase a Adagen PK Week Revcovi Tm Treatment Weeks 1 Through 21 d
Weekly Dose (U/kg)b Trough ADA Activity (mmol/hr/L) Weekly Dose (U/kg)b Trough ADA Activity (mmol/hr/L)

Erythrocyte

dAXP (mmol/L)

Total Lymphocytes (x10 9 /L) Weekly Dose (mg/kg) b No. of Trough ADA Activity Values >15 mmol/hr/L

No. of Erythrocyte

dAXP Values < 0.02 mmol/L

Total Lymphocytes (x10 9 /L)
004-001 Male/19/Other 28.2 20.9 28.2 14.5 < 0.02 0.57 0.188 13/14 13/14 0.73
005-001 Male/21/Other 29.6 < lloq 34.5c 17.6 < 0.02 0.52 0.224 12/13 13/13 0.99
005-002 Male/37/Black or African American 7.7 < lloq 30c 22.4 < 0.02 1.71 0.2 13/13 12/13 1.76
006-002 g Female/30/White 31.3 <lloq g 31.3 9.02 < 0.02 0.59 0.209 10/12 11/11 0.49
011-001 Female/16/White 42.9 11.74 42.9 16.10 < 0.02 1.17 0.285 12/13 12/12 1.39
012-001e Male/18/White 21.6 11.55 25.9c 15.44 < 0.02 0.20 0.17 8/9 8/8 0.26f