|
All Patients (N=34) |
Patients Failing Conventional Therapy (n=27) | |
| ORR, n/N (%) | 22/34 (65)* | 17/27 (63)** |
| Time to response, days (median [95% CI]) | 8.0 [5.0-10.0] | 8.0 [7.0-14.0] |
| Cumulative duration of response, % days of treatment (median [Q1, Q3]) | 75.7 [33.3-91.2] | 75.4 [30.8-91.2] |
| Proceeded to HSCT, n/N (%) | 22/34 (65) | 19/27 (70) |
| Overall Survival | ||
| Alive at last observations, n/N (%) | 24/34 (70.6) | 20/27 (74.1) |
| 12-month pOS estimate (% [95% CI]) | 69 [50-82] | 73 [52-86] |
| Survival to HSCT, n/N (%)*** | 27/34 (79.4) | 22/27 (81.5) |
| Survival post HSCT, n/N (%) | 20/22 (90.9) | 17/19 (89.5) |
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