M/F	Age at onset (years)	ALPS/ALPS-like	Symptoms	Genetic mutation	Defective lymphocyte apoptosis	sFAS-L (>200 pg/ml)	IL-10 (>20 pg/ml)	IL-18 (>500 pg/ml)	Vit B12 (n.r. 191 - 663 pg/ml)	IgG (mg/dl)	Family history	DNT (>1.5% of total lymph)	B220+ DNT (>60%)	CD3+CD25+ / CD3+HLADR+ ratio (<1%)	CD27+ (<15%)
P1	F	12	ALPS-like	+ Autoimmunity	- CASP10 - Leu522lle - CASP8 - Met1Thr (Homozygosis)	No	0	4	365	482	1407	Neg	1.7	22	0.3	84.3
P2	M	11	ALPS-like	Trilinear cytopenia + Autoimmunity + LP	- CASP10 - Leu522lle - TNFRSF13C – His159Tyr - TNFRSF13C – Pro21Arg	No	0	3	660	356	820	Neg	4	70.6	0.1	4.5
P3	F	9	ALPS-like	monolinear cytopenia + LP	- CASP10 – Val410lle	Yes (100%)	0	1,1	550	1014	1076	Neg	1.2	46	1.3	0.3
P4	F	5	ALPS P	monolinear cytopenia + LP	- CASP10 – Tyr446Cys	No	0	<1	1050	466	1094	Neg	2.3	92	0.2	15.6
P5	M	3	No	monolinear cytopenia + RRI + Recurrent skin abscesse	- CASP10 – Val410lle	ND	0	<1	75	699	1154	Neg	1.1	61.7	0.9	12.4
P6	M	2	ALPS	Asthenia + LP + RI + Arthromyalgia	- CASP10 – I406L	No	0	<1	500	583	1062	Neg	3.9	57	0.7	23.6