Table 2.

Clinical presentation, treatment and outcome of the children with neurological complications of 2009 H1N1 virus infection at Evelina Children’s Hospital

	Case 1	Case 2	Case 3	Case 4	Case 5
Age at presentation	2 years 10 months	4 years 6 months	10 years 5 months	5 years 5 months	10 months
Sex	Male	Female	Male	Female	Male
Race	African Carribean	Caucasian	Asian	Caucasian	Caucasian
Past medical history	Febrile convulsions mild speech delay	None	None	Asthma	Down’s syndrome
Duration to neurological symptoms	3 days	2 days	7 days	2 days	7 days
Seizures	+	+	+	+	−
Encephalopathy	−	+	+	+	+
Encephalitis	−	+	+	−	−
Fever, °C	38	38.9	39	40	40
Antiviral therapy	Oseltamivir	Oseltamivir, changed to zanamavir	Oseltamivir	Oseltamivir	Oseltamivir
IVIG 1 course = 1 g/kg/day for 2 days	None	1 course	3 courses, 1 month apart	1 course	None
Outcome	Level 2	Level 1	Level 3	Level 3	Level 1

IVIG intravenous immunoglobulin, + present, − absent, outcome level 1 normal resolution, level 2 mild sequelae, level 3 severe sequelae requiring personal help for daily activities, level 4 death