Fig. 1.

Effects of losartan and enalapril on dengue virus expression in peritoneal macrophages. A) Losartan and enalapril treatment resulted in a decrease in the percentage of macrophages expressing type 2 dengue virus antigens. (B and C) Immunofluorescence staining for dengue virus antigens in untreated (B) and losartan-treated (C) infected peritoneal macrophages at 12 h after infection (arrows indicate positive cells). D) Macrophages from an uninfected animal treated with losartan (arrows indicate negative cells). Positive infected cells were detected using a fluorescein-conjugated anti-DENV2-specific monoclonal antibody. Original magnification: x400