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. 2017 Sep 15;162(12):3779–3789. doi: 10.1007/s00705-017-3548-1

Table 2.

Severity of disease after passive transfer of sera and challenge with PEDV CV777

Sow group Days after challenge with PEDV strain CV777
1 2 3 4 5 6 7 8 9 10
rSPV-St ++a/+b/+c/+d +++a/+++b/+c/+d ND ND ND ND ND ND ND ND
Inactivated-CV777 a/–b/-c/-d a/–b/-c/-d a/–b/-c/-d a/–b/-c/-d a/–b/-c/-d a/–b/-c/-d a/–b/-c/-d a/–b/-c/-d a/–b/-c/-d a/–b/-c/-d
Inactivated-SQ2014 ++a/+b/+c/+d +++a/+++b/+c/+d +++a/+++b/+c/+d ND ND ND ND ND ND ND
wtSPV ++a/+b/+c/+d +++a/+++b/+c/+d ND ND ND ND ND ND ND ND
PBS ++a/+b/+c/+d +++a/++b/+c/+d ND ND ND ND ND ND ND ND

ND: not determined due to the death of this piglet

a Severity of diarrhea: – no diarrhea; + mild diarrhea; ++ moderate diarrhea; +++ severe diarrhea

b Degree of appetite loss: – normal appetite; + slight loss of appetite; ++ moderate loss of appetite; +++ no appetite

c Loss of mental stability: - mental stability; + mentally unstable

d PEDV detection in feces by RT-PCR: - negative; + positive