Fig. 2.

The inhibition of TGEV infection by IFN-γ does not depend on type I IFNs, type III IFN, or the expression of IFNGR in IPEC-J2, ST, and Vero E6 cell lines. (a, b) IFN-γ inhibits TGEV in a dose-dependent manner in Vero E6 cells or IFNLR-knockout Vero E6 cells. Cells were harvested for quantification of the TGEV genome. Asterisks indicate statistical significance relative to the no-IFN-γ control. ***, p < 0.001; ****, p < 0.0001 (c) IPEC-J2, ST, and Vero E6 cell lines were harvested after 24 h for quantification of IFNGR mRNA levels