Table 2.
Effects of rs1889570 gene polymorphism on the severity of EV71 infection
| C/C (n = 112) | C/T (n = 179) | T/T (n = 45) | p-value | |
|---|---|---|---|---|
| Male (n) | 70 | 89 | 22 | |
| Female (n) | 42 | 90 | 23 | 0.08a |
| Ages (years) | 3.9 (2.9–5.45) | 3.7 (2.3–5.2) | 3.7 (2.25–5.65) | 0.382b |
| Duration of fever (days) | 1.5 (1–2.5) | 2 (1–3) | 2.5 (1.5–4) | 0.0008b |
| WBC (× 109/L) | 7.7 (6.6–9.8) | 8 (5.8–10) | 9.2 (7.15–13.3) | 0.045b |
| CRP (mg/L) | 5.1 (2.6–8.3) | 5.8 (3–9) | 7.1 (4.85–10.2) | 0.038b |
| BG (mmol/L) | 5.4 (4.7–6.9) | 5.7 (5.1–6.8) | 6.1 (5.4–9.0) | 0.019b |
| ALT (U/L) | 18.5 (15.25–25) | 19 (15–25) | 18 (16.5–25) | 0.76b |
| AST (U/L) | 25 (20–33) | 25 (19-34) | 25 (18–35) | 0.964b |
| CK-MB (U/L) | 12 (9.25–19) | 14 (9–19) | 12 (8–19) | 0.706b |
| EV71 load (log10 copies/ul) | 4.2 (3.8–4.6) | 4.3 (3.8–6.8) | 4.3 (3.9–6.8) | 0.091b |
WBC, white blood cell count; CRP, C-reactive protein; BG, blood glucose; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, cardiac creatine kinase-MB fraction
aGroups compared using chi-square test
bValues expressed as median (25th–75th percentile values); groups compared using nonparametric test