Table 3.
RSV (n = 20) | Other respiratory (n = 30) | Non-respiratory (n = 108) | Overall p value | Post hoc tests of significant pairs | p for post hoc comparison | |
---|---|---|---|---|---|---|
Hospital admission | 10,936 (31,928) [1,895, 956–142,584] | 1,705 (1,073) [1,097, 478–5,887] | 230 (562) [0, 0–3,304] | p = 0.019 | RSV vs non-resp | 0.06 |
RSV vs other resp | 0.10 | |||||
Respiratory admission | 8,878 (31,385) [1,123, 956–142,051] | 1,211 (506) [1,087, 478–3,117] | 0 (0) [0, 0–0] | p = 0.09 | RSV vs other resp | 0.09 |
OPD visit | 931 (885) [695,126–4,092] | 900 (916) [530, 0–3,929] | 579 (435) [501, 0–2,186] | p = 0.017 | RSV vs non-resp | 0.05 |
RSV vs other resp | 0.89 | |||||
Respiratory OPD visit | 95 (221) [0, 0–882] | 180 (301) [0, 0–1,182] | 25 (157) [0, 0–1,542] | p = 0.56 | RSV vs non-resp | n/a |
RSV vs other resp | ||||||
A&E visit | 284 (158) [224, 71–606] | 273 (232) [227, 71–1,170] | 52 (102) [0, 0–694] | p = 0.003 | RSV vs non-resp | 0.03 |
RSV vs other resp | 0.93 | |||||
Respiratory A&E visit | 149 (69) [137, 46–296] | 178 (148) [149, 0–616] | 13 (61) [0, 0–585] | p = 0.38 | RSV vs non-resp | n/a3 |
RSV vs other resp | 0.38 | |||||
Prescription | 74 (102) [42, 1.7–426] | 118 (249) [38, 7.6–1,109] | 29 (28) [21, 0–125] | p = 0.001 | RSV vs non-resp | 0.04 |
RSV vs other resp | 0.22 | |||||
Respiratory prescription | 17 (22) [14, 0–90] | 63 (195) [16, 0–1,070] | 5 (12) [1.4, 0–109] | p = 0.05 | RSV vs non-resp | 0.21 |
RSV vs other resp | 0.11 | |||||
Total costs | 12,505 (32,137) [2,939, 1,648–144,034] | 3,356 (2,121) [2,410, 1,279–9,111] | 1,178 (940) [900, 32–5,066] | p < 0.001 | RSV vs non-resp | <0.001 |
RSV vs other resp | 0.005 | |||||
Total respiratory admission costs | 9,273 (31,409) [1,570, 1,088–142,498] | 1,815 (1,192) [1,472, 515–5,896] | 80 (186) [0, 0–1,565] | p = 0.011 | RSV vs non-resp | 0.05 |
RSV vs other resp | 0.12 | |||||
Total respiratory minus index respiratory admission | 1,342 (3,239) [459, 0–14,858] | 647 (977) [359, 0–4,940] | 80 (186) [0, 0–1,565] | p = 0.016 | RSV vs non-resp | 0.06 |
RSV vs other resp | 0.33 |
Data are demonstrated as mean (SD) [median, range]. All analyses use a generalised linear model with gamma distribution and identity link. In the final column: for statistical significance, p must be less than 0.017 to account for multiple testing. For 97/128 subjects in the ‘non-respiratory’ group, the total cost was zero and so the model would not permit this group to be included. Hence, the comparison RSV vs other respiratory only has been included for this variable. Mean costs should be used in any calculations to obtain total costs and not medians