Table 2.
Carbohydrate receptors targeted by DENV on mammalian and insect cells
| Molecule | Type | Cell type | Serotype | References |
|---|---|---|---|---|
| DC-SIGN | C-type lectin | Monocyte-derived dendritic cells | DENV 1, 2, 3, and 4 | [71] |
| Heparan sulfate | Glycosaminoglycans |
Vero CHO K1 |
DENV 2 | [72] |
| nLc4Cer | Glycosphingolipid |
K562 BHK-21 LLC-MK2 |
DENV 2 | [73, 74] |
| Mannose receptor | Protein |
NIH3T3 Monocytes Macrophages |
DENV 1, 2, 3, and 4 | [75] |
| High-affinity laminin receptor | Protein |
HepG2 PS clone D |
DENV 1, 2 and 3 | [68, 76] |
| CLEC5A | C-type lectin | Macrophages | DENV 1, 2, 3, and 4 | [77] |
| L-3 | Glycosphingolipid | AP-61 | DENV 2 | [74] |
| 40- and 45-kDa glycoproteins | Glycoprotein | C6/36 cells | DENV 4 | [78–80] |