Table 3.
Cox models
| Variables | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age > 65 years | 2.4 (1.6–3.6) | < 0.001 | ||
| Surgical complexity | 0.104 | – | – | |
| Low | Ref | |||
| Intermediate | 1.2 (0.7–2.3) | |||
| High | 0.5 (0.3–1.0) | |||
| CA 125 > 500 | 1.0 (0.6–1.6) | 0.96 | – | – |
| Chemotherapy only | Ref | < 0.001 | ||
| NACT– IDS | 0.2 (0.1–0.3) | 0.48 (0.22–1.01) | 0.054 | |
| PDS | 0.1 (0.1–0.2) | 0.32 (0.14–0.71) | 0.005 | |
| Postoperative residual disease > 0 | Ref | < 0.001 | ||
| Postoperative residual disease = 0 (complete surgery) | 0.2 (0.20–0.21) | 0.37 (0.18–0.75) | 0.006 | |
| Association of Carboplatin and Paclitaxel | 0.4 (0.2–0.56) | < 0.001 | 0.45 (0.25–0.80) | 0.007 |
| Metastatic locations | ||||
| Hepatic | 1.3 (0.8–2.1) | 0.213 | – | – |
| Pleural effusion | 1.5 (1.0–2.3) | 0.0658 | – | – |
| Solid pleural lesion | 1.2 (0.6–2.6) | 0.576 | – | – |
| Supra-diaphragmatic lesion | 1.1 (0.7–1.8) | 0.693 | – | – |
| Deep intra—abdominal organ | 0.5 (0.2–0.95) | 0.0209 | ||
Univariable and multivariable analysis of the factors influencing overall survival in patients with stage IV epithelial ovarian cancer