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Education‐based interventions forcoronary heart disease
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Patient or population: people with CHD
Settings:
Intervention: education‐based interventions |
| Outcomes |
Illustrative comparative risks* (95% CI) |
Relative effect
(95% CI) |
No of participants
(studies) |
Quality of the evidence
(GRADE) |
Comments |
| Assumed risk |
Corresponding risk |
| |
Control |
Education‐based interventions |
|
|
|
|
|
Total mortality
deaths
Follow‐up: median 18 months |
Study population |
RR 0.79
(0.55 to 1.13) |
2330
(6 studies) |
⊕⊕⊕⊝
moderate1
|
‐ |
| 96 per 1000 |
76 per 1000
(53 to 108) |
|
| Moderate |
|
| ‐ |
‐ |
|
| Hospitalisations |
Study population |
RR 0.83
(0.65 to 1.07) |
12,905
(4 studies) |
⊕⊕⊕⊝
moderate1
|
‐ |
| 64 per 1000 |
53 per 1000
(41 to 68) |
|
| Moderate |
|
| ‐ |
‐ |
|
| MI |
Study population |
RR 0.63
(0.26 to 1.48) |
209
(2 studies) |
⊕⊝⊝⊝
very low2
|
‐ |
| 118 per 1000 |
74 per 1000
(31 to 174) |
|
| Moderate |
|
| ‐ |
‐ |
|
| CABG |
Study population |
RR 0.58
(0.19 to 1.71) |
209
(2 studies) |
⊕⊕⊝⊝
low2
|
‐ |
| 78 per 1000 |
45 per 1000
(15 to 134) |
|
| Moderate |
|
| ‐ |
‐ |
|
| All‐cause withdrawal |
Study population |
RR 1.03
(0.83 to 1.27) |
2862
(8 studies) |
⊕⊕⊕⊝
moderate1
|
‐ |
| 181 per 1000 |
186 per 1000
(150 to 230) |
|
| Moderate |
|
| ‐ |
‐ |
|
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CABG: coronary artery bypass graft; CHD: coronary heart disease; CI: confidence interval; MI: myocardial infarction; RR: risk ratio. |
| GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate. |
|
1 The 95% CIs include both no effect and appreciable benefit or harm (i.e. RR < 0.75 or > 1.25).
2 The 95% CIs include both no effect and substantial benefit or harm (i.e. RR < 0.50 or > 1.50). |
