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. 2014 Dec 12;2014(12):CD011273. doi: 10.1002/14651858.CD011273.pub2

9. Home‐based cardiac rehabilitation compared with centre‐based cardiac rehabilitation for heart disease.

Home‐based cardiac rehabilitation compared with centre‐based cardiac rehabilitation for heart disease
Patient or population: people with heart disease
Settings:Intervention: home‐based CR
Comparison: centre‐based CR
Outcomes Illustrative comparative risks* (95% CI) Relative effect
(95% CI) No of participants
(studies) Quality of the evidence
(GRADE) Comments
Assumed risk Corresponding risk
  Centre‐based CR Home‐based CR        
Total mortality
Follow‐up: 3‐12 months Study population RR 0.79 
(0.43 to 1.47) 1166
(7 studies) ⊕⊕⊝⊝
low1,2
27 per 1000 22 per 1000
(12 to 40)  
Moderate  
 
All‐cause withdrawal
Follow‐up: median 6 months Study population RR 1.04 
(1.01 to 1.07) 1984
(18 studies) ⊕⊕⊕⊝
moderate1
874 per 1000 909 per 1000
(883 to 936)  
Moderate  
 
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; CR: cardiac rehabilitation; RR: risk ratio.
GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.
1 Random sequence generation and allocation concealment were poorly described; bias likely.
2 The 95% CIs include both no effect and appreciable benefit or harm (i.e. RR < 0.75 or > 1.25).