Table 2. KEGG pathway enrichment for the genes in the coexpression modules of MCL.
| Term | Count | Percentage | p Value | |
|---|---|---|---|---|
| Module black | hsa05133: Pertussis | 9 | 7.438016529 | 2.87759E−07 |
| hsa04062: Chemokine signaling pathway | 12 | 9.917355372 | 6.4214E−07 | |
| hsa04060: Cytokine–cytokine receptor interaction | 12 | 9.917355372 | 8.78906E−06 | |
| hsa05150: Staphylococcus aureus infection | 6 | 4.958677686 | 0.00011374 | |
| hsa05340: Primary immunodeficiency | 5 | 4.132231405 | 0.00022661 | |
| Module blue | hsa03010: Ribosome | 74 | 4.622111181 | 2.2086E−40 |
| hsa00190: Oxidative phosphorylation | 49 | 3.060587133 | 1.25281E−17 | |
| hsa05012: Parkinson’s disease | 50 | 3.123048095 | 4.75678E−17 | |
| hsa05016: Huntington’s disease | 56 | 3.497813866 | 7.26902E−15 | |
| hsa03050: Proteasome | 21 | 1.3116802 | 3.86976E−10 | |
| Module brown | hsa04110: Cell cycle | 17 | 4.473684211 | 5.56038E−08 |
| hsa03030: DNA replication | 10 | 2.631578947 | 1.55272E−07 | |
| hsa00240: Pyrimidine metabolism | 13 | 3.421052632 | 6.60428E−06 | |
| hsa01100: Metabolic pathways | 48 | 12.63157895 | 0.000894963 | |
| hsa03420: Nucleotide excision repair | 7 | 1.842105263 | 0.000996474 | |
| Module red | hsa05110: Vibrio cholerae infection | 5 | 2.564102564 | 0.006215548 |
| hsa04142: Lysosome | 7 | 3.58974359 | 0.007386343 | |
| hsa04721: Synaptic vesicle cycle | 5 | 2.564102564 | 0.012146872 | |
| hsa05120: Epithelial cell signaling in Helicobacter pylori infection | 5 | 2.564102564 | 0.014972709 | |
| hsa05168: Herpes simplex infection | 8 | 4.102564103 | 0.01521917 | |
| Module turquoise | hsa03040: Spliceosome | 36 | 2.297383535 | 1.93556E−09 |
| hsa05169: Epstein–Barr virus infection | 28 | 1.786853861 | 5.54839E−06 | |
| hsa04144: Endocytosis | 43 | 2.744097001 | 1.19036E−05 | |
| hsa04662: B cell receptor signaling pathway | 19 | 1.212507977 | 1.97499E−5 | |
| hsa03030: DNA replication | 13 | 0.829610721 | 3.50627E−05 | |
| Module yellow | hsa03040: Spliceosome | 9 | 3.75 | 0.00053903 |
| hsa05203: Viral carcinogenesis | 9 | 3.75 | 0.008102343 | |
| hsa05166: HTLV-I infection | 10 | 4.166666667 | 0.009303826 | |
| hsa05200: Pathways in cancer | 12 | 5 | 0.021866894 | |
| hsa04151: PI3K–Akt signaling pathway | 11 | 4.583333333 | 0.022950705 |
Note:
KEGG, Kyoto Encyclopedia of Genes and Genomes; HTLV-I, Human T-cell leukemia virus type 1; PI3K, Phosphatidylinositol-3-kinase; Akt, protein kinase B.