Table 8.
Examples of Antibacterial and Antifungal Products from Sponges
| Compound | Compound class | Species/order | Activity | Reference |
|---|---|---|---|---|
| Discodermins B, C, and D | Cyclic peptide | Discodermia kiiensis/Lithistida | Antibacterial | Matsunaga et al., 1985 |
| Topsentiasterol sulfates A–E | Sulfated sterol | Topsentia sp./Halichondrida | Antibacterial/antifungal (D and E) | Fusetani et al., 1994 |
| Arenosclerins A, B, and C | Alkylpiperidine alkaloid | Arenosclera brasiliensis /Haplosclerida | Antibacterial | Torres et al., 2002 |
| Axinellamines B–D | Imidazo-azolo-imidazole alkaloid | Axinella sp./Halichondrida | Antibacterial | Urban et al., 1999 |
| Acanthosterol I and J | Sulfated sterol | Acanthodendrilla sp./Dendroceratida | Antifungal | Tsukamoto et al., 1998 |
| Oceanapiside | Bisaminohydroxylipid glycoside | Oceanapia phillipensis/Haplosclerida | Antifungal | Nicolas et al., 1999 |
| Spongistatin | Polyether macrolide lactone | Hyrtios erecta/Dictyoceratida | Antifungal | Pettit et al., 1998 |
| Leucascandrolide A | Oxazole-containing polyether macrolide | Leucascandra caveolata/Calcarea | Antifungal | D’Ambrosio et al., 1996 |