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. 2012 Feb 15;34(5):831–838. doi: 10.1007/s10529-011-0845-8

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© Springer Science+Business Media B.V. 2012

This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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Fig. 3 — Lineweaver-Burk plot (a) and Dixon plot (b) analyses for the inhibition of 3CL^pro by GCG. The kinetic constants, K _m and K _i, were calculated using linear regression analysis. a GCG concentration 0 μM (filled circle), 20 μM (open circle), 30 μM (filled inverted triangle), 40 μM (open triangle), 50 μM (filled square), 60 μM (open square). b FRET substrate concentrations 5 μM (filled circle), 7.5 μM (open circle), 10 μM (filled inverted triangle), and 15 μM (triangle)