Table 2.
EXP-ID | Immunogen | DA substrains | Incidence of arthritis | Day of onset (mean ± SD)a | Maximal arthritis score (mean ± SD)a |
---|---|---|---|---|---|
EXP-01 | 50 μl pristane | DA/OlaHsd | 25/26 | 12 ± 2 | 39 ± 11 |
DA/ZtmRhd | 13/27* | 14 ± 2* | 25 ± 11* | ||
EXP-02 | 50 μl pristane | DA/OlaHsd | 26/29 | 12 ± 2 | 46 ± 9 |
DA/ZtmRhd | 13/27* | 12 ± 1 | 40 ± 8* | ||
EXP-03b | 150 μl pristane | DA/ZtmRhd | 9/10 | 13 ± 2 | 27 ± 14 |
EXP-04 | 75 μg CII/100 μl | DA/OlaHsd | 20/20 | 15 ± 2 | 36 ± 18 |
DA/ZtmRhd | 20/22 | 18 ± 3* | 21 ± 15* | ||
EXP-05 | 75 μg CII/100 μl | DA/OlaHsd | 18/19 | 14 ± 1 | 53 ± 10 |
DA/ZtmRhd | 17/17 | 16 ± 2* | 33 ± 17* |
SD = standard deviation
aOnly affected animals included
bExperiment was terminated at day 16
* Significantly different (p < 0.05) from DA/OlaHsd