Table 1.
Serial detection of SARS-CoV RNA and antibodies against SARS-CoV in the plasma of 25 hospitalized patients with a clinical diagnosis of SARS
| Pt. no. | Age (year) | Sex | Course (day) | Manifestation or result | Day after disease onset (IgM/IgG/RNA) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1–7 | 8–14 | 15–21 | 22–28 | 29–35 | 36–42 | 43–49 | 50–56 | |||||
| 1 | 20 | M | 77 | Critical | ND | ND | −/−/+ | −/−/+ | +/+/+ | +/+/+ | +/+/+ | +/+/− |
| 2 | 27 | M | 34 | General | −/−/− | +/+/− | +/+/− | +/+/− | +/+/− | |||
| 3 | 42 | F | 73 | Critical | ND | −/−/+ | −/+/− | +/+/− | +/+/− | +/+/− | +/+/− | −/+/− |
| 4 | 59 | M | 73 | Critical | ND | +/+/+ | +/+/− | +/+/− | +/+/− | +/+/− | +/+/− | −/+/− |
| 5 | 39 | M | 41 | General | −/−/− | +/+/+ | −/+/− | −/+/− | −/+/− | −/+/− | ||
| 6 | 33 | M | 59 | General | ND | −/+/+ | +/+/− | +/+/− | +/+/− | +/+/− | +/+/− | +/+/− |
| 7 | 51 | M | 59 | Dead | ND | −/+/+ | +/+/− | +/+/− | +/+/− | −/+/− | −/+/− | −/+/− |
| 8 | 26 | M | 41 | General | ND | +/+/− | +/+/− | +/+/− | +/+/− | +/+/− | ||
| 9 | 32 | M | 30 | General | −/−/− | −/−/− | −/−/− | −/−/− | −/−/− | |||
| 10 | 31 | F | 47 | Critical | −/−/− | −/−/+ | +/+/+ | +/+/+ | −/+/+ | −/+/− | −/+/− | |
| 11 | 19 | F | 59 | General | ND | −/−/+ | −/−/+ | +/+/− | +/+/− | +/+/− | +/+/− | +/+/− |
| 12 | 31 | M | 50 | Critical | ND | −/+/− | +/+/− | +/+/− | +/+/− | +/+/− | −/+/− | −/+/− |
| 13 | 42 | M | 49 | Critical | ND | −/−/− | −/−/− | +/+/− | +/+/− | +/+/− | +/+/− | |
| 14 | 13 | F | 34 | General | −/−/− | −/−/− | −/−/− | −/−/− | −/−/− | |||
| 15 | 45 | F | 31 | General | −/−/− | −/−/− | +/−/− | +/+/− | +/+/− | |||
| 16 | 46 | F | 36 | Critical | −/−/− | −/−/+ | −/−/+ | −/−/+ | −/+/− | +/+/− | ||
| 17 | 33 | M | 41 | Critical | ND | −/+/− | ND | +/+/− | +/+/− | +/+/− | ||
| 18 | 38 | F | 36 | General | −/−/− | −/−/− | +/−/− | +/−/− | +/−/− | −/−/− | ||
| 19 | 21 | M | 67 | Critical | −/−/− | −/−/− | +/+/− | +/+/− | +/+/− | +/+/− | +/+/− | ND |
| 20 | 20 | M | 38 | General | −/−/− | −/−/− | −/−/− | −/−/− | −/−/− | −/−/− | ||
| 21 | 48 | M | 38 | Critical | −/−/+ | +/−/+ | +/+/− | +/+/− | +/+/− | +/+/− | ||
| 22 | 9 | M | 36 | General | −/−/− | −/−/+ | −/−/− | −/−/+ | −/−/− | −/−/− | ||
| 23 | 45 | M | 30 | General | ND | −/−/− | −/+/− | −/+/− | ND | |||
| 24 | 32 | M | 47 | General | −/−/+ | +/+/+ | +/+/− | +/+/− | +/+/− | +/+/− | ND | |
| 25 | 18 | M | 46 | General | ND | +/−/− | +/−/− | +/+/− | +/+/− | +/+/− | +/+/− | |
M, male; F, female; +, positive; −, negative; ND, not detected