Table 1.
Anti-protease activities of crude extracts from actinomycete and sphingomonad strains grown on M1 media and extracted at different time points (4, 7, 14, and 21 days)
Strain | % protease inhibition | |||
---|---|---|---|---|
Cathepsin B | Cathepsin L | Falcipain-2 | Rhodesain | |
Actinomycetes | ||||
Nocardioides sp. BA21a | ND | ND | ND | 40 ± 1e |
Agrococcus jenensis strain BA22 | 41 ± 1c | ND | 44 ± 2b, 40 ± 4e | ND |
Micromonospora coxensis strain CO74 | ND | ND | 42 ± 2c | ND |
Saccharopolyspora shandongensis strain CO86 | ND | ND | ND | 52 ± 1d |
Rhodococcus sp. CO155a | ND | 44 ± 4d | ND | ND |
Micromonospora coxensis strain CO164 | 45 ± 3b | 43 ± 2d | 41 ± 2d | 46 ± 3b, 57 ± 5c |
Sphingomonads | ||||
Sphingobium sp. CO132a | ND | ND | ND | 53 ± 3d |
Sphingomonas mucosissima strain CO180 | 49 ± 5b | ND | 45 ± 1d | ND |
Samples were tested in duplicates at a concentration of 20 μg/ml
ND Not detected
aPutatively novel species
b4 days
c21 days
d7 days
e14 days