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Superimposition of the sialic acid portion of a set of conformations of Neu5,9Ac2α(2–6)-S-Glcβ1Me (4) with the methyl 9-acetamido-9-deoxy-N-acetyl-α-D-neuraminide (9-acetamido-9-deoxy-Neu5Acα2Me, 6) within the active site of INF-C HEF. The glucose moiety of 6 does not interact with the protein surface and more likely has no effect on acetate cleavage and release
