Table 3:
Maternal Characteristics | All-cause mortality** | Mortality (Excluding External causes)*** | ||
---|---|---|---|---|
Unadjusted HR (95% CI) | Adjusted HR† (95% CI) | Unadjusted HR (95% CI) | Adjusted HR† (95% CI) | |
Fertility Group | ||||
Fertile | Reference | Reference | Reference | Reference |
Subfertile | 0.58 (0.37–0.93) | 0.89 (0.56–1.42) | 0.68 (0.38–1.2) | 0.75 (0.42–1.33) |
ART | 0.46 (0.3–0.72) | 0.75 (0.48–1.18) | 0.73 (0.46–1.16) | 0.81 (0.50–1.30) |
Mother’s Age (years) at last delivery | ||||
<25 | Reference | Reference | Reference | Reference |
25–29 | 0.75 (0.64–0.88) | 1.15 (0.98–1.35) | 1.08 (0.84–1.38) | 1.49 (1.16–1.91) |
30–34 | 0.56 (0.48–0.65) | 1.31 (1.11–1.55) | 1.08 (0.86–1.36) | 2.04 (1.59–2.61) |
35–39 | 0.66 (0.56–0.78) | 1.68 (1.4–2.01) | 1.46 (1.16–1.83) | 2.85 (2.21–3.67) |
40+ | 0.77 (0.61–0.98) | 1.81 (1.41–2.32) | 1.82 (1.35–2.45) | 3.23 (2.35–4.44) |
Race/Ethnicity | ||||
Non-Hispanic White | Reference | Reference | Reference | Reference |
Hispanic | 0.65 (0.55–0.78) | 0.34 (0.28–0.41) | 0.76 (0.6–0.95) | 0.5 (0.39–0.63) |
Non-Hispanic Black | 1.04 (0.87–1.25) | 0.54 (0.45–0.65) | 1.24 (0.99–1.55) | 0.71 (0.56–0.9) |
Asian/Pacific Islanders | 0.38 (0.28–0.51) | 0.48 (0.36–0.65) | 0.54 (0.39–0.76) | 0.65 (0.46–0.91) |
American Indians & Others | 1.00 (0.69–1.44) | 0.64 (0.45–0.93) | 0.96 (0.58–1.58) | 0.71 (0.43–1.17) |
Education | ||||
<HS or HS/GED | Reference | Reference | Reference | Reference |
Some college or Associate Degree | 0.73 (0.62–0.86) | 0.87 (0.73–1.03) | 0.79 (0.63–0.98) | 0.81 (0.64–1.01) |
Bachelor’s degree or Post-graduate | 0.31 (0.27–0.36) | 0.54 (0.45–0.64) | 0.48 (0.41–0.57) | 0.59 (0.48–0.73) |
Marital Status | ||||
Married | Reference | Reference | Reference | Reference |
Not Married | 3.22 (2.88–3.6) | 2.38 (2.06–2.73) | 1.98 (1.72–2.29) | 1.84 (1.54–2.21) |
Insurance at last delivery | ||||
Private | Reference | Reference | Reference | Reference |
Public | 2.85 (2.54–3.2) | 1.84 (1.58–2.14) | 1.83 (1.58–2.11) | 1.49 (1.23–1.80) |
History of Chronic Hypertension | ||||
No | Reference | Reference | Reference | Reference |
Yes | 3.47 (2.99–4.02) | 2.43 (2.06–2.86) | 4.77 (4–5.69) | 3.22 (2.65–3.92) |
Pregnancy Hypertension/Eclampsia/Preeclampsia | ||||
No | Reference | Reference | Reference | Reference |
Yes | 1.50 (1.21–1.86) | 1.15 (0.92–1.43) | 1.77 (1.35–2.3) | 1.2 (0.91–1.58) |
History of Chronic Diabetes | ||||
No | Reference | Reference | Reference | Reference |
Yes | 3.26 (2.66–4.00) | 1.92 (1.54–2.38) | 0.58 (0.37–0.93) | 1.94 (1.49–2.54) |
Adjusted analyses of factors associated with all-cause mortality and mortality excluding external causes are shown in Table 3. The strongest parameters predicting all-cause mortality were history of mother’s age, education, marital status, and being publically insured as well as chronic hypertension, chronic diabetes. Once adjusted, fertility group (ART, subfertility) is no longer a significant predictor of all-cause mortality. Hazard ratios in bold denote significant results at P<0.05.
Study sample for all-cause-mortality is based on (N=480,243). Missing covariates for education (n=1568), Race (N=527), and marital status (N=1457) were deleted for modeling purposes.
Study sample for mortality (excluding external causes) is based on (N= 479,693). Missing covariates for education (N=1568), Race (N=525), and marital status (N=1453) and external causes of death (N=555) were deleted for modeling purposes.
Models are simultaneously adjusted for all other maternal characteristics included in table 3.