Table 3.
Nucleotide changes in RGCB isolates with respect to S-27 reference strain
| Sl. no. | Isolate | Year of collection | GenBank accession no. | Number of nucleotide changes | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coding region (synonymous/non-synonymous) | 5′NTR | 3′NTR | ||||||||||||
| Non-structural protein | Structural protein | |||||||||||||
| nsP1 | nsP2 | nsP3 | nsP4 | C | E3 | E2 | 6K | E1 | ||||||
| 1 | RGCB03/KL06 | 2006 | GQ428210 | 31/9 | 51/5 | 47/12 | 44/7 | 16/3 | 3/1 | 29/15 | 2/2 | 28/6 | 1 | 16 |
| 2 | RGCB05/KL06 | 2006 | GQ428211 | 32/9 | 50/5 | 48/12 | 42/6 | 15/4 | 3/1 | 31/14 | 2/2 | 28/4 | 1 | 17 |
| 3 | RGCB80/KL07 | 2007 | GQ428212 | 33/10 | 55/9 | 47/12 | 42/7 | 16/3 | 3/1 | 31/15 | 2/2 | 29/5 | 1 | 19 |
| 4 | RGCB120/KL07 | 2007 | GQ428213 | 33/9 | 49/8 | 48/11 | 44/6 | 16/3 | 3/1 | 32/17 | 2/3 | 29/5 | 1 | 19 |
| 5 | RGCB355/KL08 | 2008 | GQ428214 | 33/9 | 51/7 | 50/13 | 45/9 | 16/3 | 3/1 | 31/16 | 2/2 | 29/6 | 1 | 19 |
| 6 | RGCB356/KL08 | 2008 | GQ428215 | 35/10 | 52/6 | 47/12 | 42/6 | 16/2 | 3/2 | 29/17 | 2/2 | 28/6 | 1 | 17 |