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shRNA constructs interfere with PDCoV production in ST cells. TCID50 was calculated by the Reed–Muench method 48 h after infection. Virus yields were measured from TCID50. The data shown represent the means of three experiments. Error bars show the SD either ****P < 0.0001 pGenesil-M and pGenesil-N each compared with the negative control. *P < 0.05 pGenesil-M compared to pGenesil-N
