. 2019 Feb 15;55(3):415–420. doi: 10.1007/s11262-019-01647-1

Table 1.

Mean estimations for the rate of evolution and tMRCAs and positively selected sites of different lineages for BCoV spike genes

Lineage	Substitution rate (× 10⁻⁴ subs/site/year)			TMRCA (calendar year)			Omega value (dN/dS)	Positively selected sites (p > 95%; ^*p > 99%)
Lineage	Mean	95% HPD lower	95% HPD upper	Mean	95% HPD lower	95% HPD upper	Omega value (dN/dS)	NEB	BEB
BCoV	3.2013	2.3252	4.1831	1937	1922	1951	-	-	-
C1	7.6206	6.2199	9.1537	1962	1950	1973	0.15734	11, 179^, 499, 501^, 1352	11^, 179^,256, 412, 499^, 501^, 716, 1352^*
C2	5.479	3.9751	6.9255	1948	1928	1964	0.11613	35, 113^, 501^, 525^*	23, 35^, 113^, 118, 257, 501^, 525^, 540, 590
C3	69.803	1.2717	15.65	1943	1932	1954	1.90805	40^, 175, 179^, 253^, 484^, 906	40^, 175, 179^, 253^*, 484, 905
V	-	-	-	1962	1950	1973	0.10297	-	-

V Vietnam BCoV strains, NEB naive empirical bayes analysis, BEB bayes empirical bayes analysis, - not test

*Positively selected sites identified with posterior probability > 99% level