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. 2019 Dec 30;3(1):107–118. doi: 10.1021/acsptsci.9b00087

Table 1. Types of Ribosome-Inactivating Proteins and Their Molecular Targets.

type of RIP samples target ref
type I RIP tricosanthin depurinates A4324 positioned in the conserved α-sarcin/ricin loop (4)
gelonin depurinates A4324 positioned in the conserved α-sarcin/ricin loop (5)
depurinates poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase (6)
saporin depurinates A4324 positioned in the conserved α-sarcin/ricin loop (7)
depurinates poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase (6)
momordin depurinates A4324 positioned in the conserved α-sarcin/ricin loop (8)
depurinates poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase (6)
PAP removes A4324, A4321, and G4323 from the eukaryotic large rRNA (9)
type II RIP ricin modifies both or either G4323 and A4324 nucleoside residues (10)
depurinates poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase (6)
agglutinin depurinates A4324 nucleoside residue (11)
abrin modifies both or either G4323 and A4324 nucleoside residues (10)
modeccin modifies both or either G4323 and A4324 nucleoside residues (10)