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. 2017 Mar 10;17(3):16. doi: 10.1007/s11882-017-0685-2

Table 2.

Characterization of hPIV common structural proteins

Localisation Protein Function
Associated with vRNA (nucleocapsid formation) L RNA-dependent RNA polymerase
P Phosphoprotein subunit of the RNA-dependent RNA polymerase
N Nucleocapsid protein
Surface glycoproteins HN Haemagglutinin-neuraminidase, found on the lipid envelope of hPIV and infected cells, functions in virus-host cell attachment via sialic acid receptors
F Fusion protein that allows the viral nucleocapsid to enter and infect a host cell; required for membrane fusion between host cells (syncytial formation)
M Matrix protein with a role in attaching nucleocapsids to areas of the infected cell membrane, generating the viral envelope; may be involved in viral budding