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Impact of LV-delivered shRNAs on HBV core protein levels. HepG2.2.15 cells were transduced with the indicated LV-HBV-shRNA vectors as described in Fig. 4. Untreated HepG2.2.15 cells served as reference. Core protein in cellular lysates was detected by immunoblotting with a HBV core specific monoclonal antibody. Detection of cellular GAPDH present in the same samples served as loading control
