Table 2.
Genotype and allele frequencies of IFITM3 gene polymorphisms in chickens
| Polymorphism | Breeds | Genotype frequency, n (%) | P value | Allele frequency, n (%) | P value | HWE | |||
|---|---|---|---|---|---|---|---|---|---|
| c.-338G > A | GG | GA | AA | G | A | ||||
| Dekalb White | 26 (24.07) | 56 (51.85) | 26 (24.07) | P < 0.001 | 108 (50) | 108 (50) | 1.0 | 0.7003 | |
| Ross | 31 (43.06) | 10 (13.89) | 31 (43.06) | 72 (50) | 72 (50) | P < 0.0001 | |||
| c.-330G > C | GG | GC | CC | G | C | ||||
| Dekalb White | 26 (24.07) | 56 (51.85) | 26 (24.07) | P < 0.0001 | 108 (50) | 108 (50) | P < 0.0001 | 0.7003 | |
| Ross | 12 (16.67) | 6 (8.33) | 54 (75) | 30 (20.83) | 114 (79.17) | P < 0.0001 | |||
| c.-295G > T | GG | GT | TT | G | T | ||||
| Dekalb White | 108 (100) | 0 (0) | 0 (0) | P < 0.0001 | 216 (100) | 0 (0) | P < 0.0001 | – | |
| Ross | 56 (77.78) | 12 (16.67) | 4 (5.56) | 124 (86.11) | 20 (13.89) | 0.0101 | |||
| c.213 + 18G > T | GG | GT | TT | G | T | ||||
| Dekalb White | 28 (25.93) | 54 (50) | 26 (24.07) | P < 0.0001 | 110 (50.93) | 106 (49.07) | P < 0.0001 | 0.9972 | |
| Ross | 49 (68.06) | 8 (11.11) | 15 (20.83) | 106 (73.61) | 38 (26.39) | P < 0.0001 | |||
| c.214-5C > T | CC | CT | TT | C | T | ||||
| Dekalb White | 108 (100) | 0 (0) | 0 (0) | P < 0.0001 | 216 (100) | 0 (0) | P < 0.0001 | – | |
| Ross | 38 (52.78) | 6 (8.33) | 28 (38.89) | 82 (56.94) | 62 (43.06) | P < 0.0001 | |||
| c.298C > A | CC | CA | AA | C | A | ||||
| (L100 M) | Dekalb White | 102 (94.44) | 6 (5.56) | 0 (0) | 0.2454 | 210 (97.22) | 6 (2.78) | 0.2502 | 0.7665 |
| Ross | 71 (98.61) | 1 (1.39) | 0 (0) | 143 (99.31) | 1 (0.69) | 0.9527 | |||
| c.307G > A | GG | GA | AA | G | A | ||||
| (V103I) | Dekalb White | 58 (53.7) | 27 (25) | 23 (21.3) | P < 0.0001 | 143 (66.2) | 73 (33.8) | P < 0.0001 | P < 0.001 |
| Ross | 19 (26.39) | 9 (12.5) | 44 (61.11) | 47 (32.64) | 97 (67.36) | P < 0.0001 | |||
| c.373A > C | AA | AC | CC | A | C | ||||
| (N125H) | Dekalb White | 108 (100) | 0 (0) | 0 (0) | 0.0624 | 216 (100) | 0 (0) | 0.0632 | – |
| Ross | 69 (95.83) | 3 (4.17) | 0 (0) | 141 (97.92) | 3 (2.08) | 0.8567 | |||
| c.444G > A | GG | GA | AA | G | A | ||||
| Dekalb White | 104 (96.3) | 4 (3.7) | 0 (0) | 0.151 | 212 (98.15) | 4 (1.85) | 0.1531 | 0.8446 | |
| Ross | 72 (100) | 0 (0) | 0 (0) | 144 (100) | 0 (0) | – | |||
| c.493A > C | AA | AC | CC | A | C | ||||
| Dekalb White | 91 (84.26) | 10 (9.26) | 7 (6.48) | 0.0664 | 192 (88.89) | 24 (11.11) | P < 0.01 | P < 0.001 | |
| Ross | 67 (93.06) | 5 (6.94) | 0 (0) | 139 (96.53) | 5 (3.47) | 0.7602 | |||
| c.657 + 29 T > G | TT | TG | GG | T | G | ||||
| Dekalb White | 47 (43.52) | 28 (25.93) | 33 (30.56) | P < 0.0001 | 122 (56.48) | 94 (43.52) | P < 0.0001 | P < 0.001 | |
| Ross | 14 (19.44) | 4 (5.56) | 54 (75) | 32 (22.22) | 112 (77.78) | P < 0.0001 | |||
| c.657 + 47_657 + 48 InsAG | Wt/Wt | Wt/Ins | Ins/Ins | Wt | Ins | ||||
| Dekalb White | 76 (70.37) | 20 (18.52) | 12 (11.11) | P < 0.0001 | 172 (79.63) | 44 (20.37) | P < 0.0001 | P < 0.001 | |
| Ross | 71 (98.61) | 0 (0) | 1 (1.39) | 142 (98.61) | 2 (1.39) | P < 0.0001 | |||
| c.657 + 47C > A | CC | CA | AA | G | C | ||||
| Dekalb White | 101 (93.52) | 7 (6.48) | 0 (0) | 0.0966 | 209 (96.76) | 7 (3.24) | 0.7456 | 0.7278 | |
| Ross | 70 (97.22) | 1 (1.39) | 1 (1.39) | 141 (97.92) | 3 (2.08) | P < 0.0001 | |||
| c.657 + 64 T > C | TT | TC | CC | T | C | ||||
| Dekalb White | 78 (72.22) | 6 (5.56) | 24 (22.22) | P < 0.001 | 162 (75.00) | 54 (25.00) | P < 0.0001 | P < 0.001 | |
| Ross | 65 (90.28) | 5 (6.94) | 2 (2.78) | 135 (93.75) | 9 (6.25) | P < 0.001 | |||