Table 2.
Enzymatic pp1a/pp1b sites and characteristics of IBV strain Sczy3 nonstructural proteins
| Cleavage Products | Position on polyprotein | C-end cleavage | Size (amino acid) | Cleavage by |
|---|---|---|---|---|
| Nsp2 | M1–G674 | AG/GK | 674 | Plpro |
| Nsp3 | G675–G2264 | AG/GV | 590 | Plpro |
| Nsp4 | G2265–Q2778 | LQ/AG | 514 | Plpro |
| Nsp5 | A2779–Q3085 | LQ/SS | 307 | Mpro |
| Nsp6 | S3086–Q3379 | VQ/SK | 294 | Mpro |
| Nsp7 | S3380–Q3462 | LQ/SV | 83 | Mpro |
| Nsp8 | S3463–Q3672 | LQ/NN | 210 | Mpro |
| Nsp9 | N3673–Q3783 | LQ/SK | 111 | Mpro |
| Nsp10 | S3784–Q3928 | VQ/SD | 145 | Mpro |
| Nsp11 | S3929–G3951 | – | 23 | Mpro |
| Nsp12 | S3929–Q4868 | LQ/SC | 940 | Mpro |
| Nsp13 | S4869–Q5468 | LQ/GT | 600 | Mpro |
| Nsp14 | G5469–Q5989 | LQ/SI | 521 | Mpro |
| Nsp15 | S5960–Q6327 | LQ/SA | 338 | Mpro |
| Nsp16 | S6327–M6629 | – | 302 | Mpro |
A alanine, C cysteine, D aspartic acid, G glycine, I isoleucine, K Lysine, L leucine, M methionine, N asparagine, Q glutamine, S serine, T threonine, V valine