Classic clinical criteria |
Fever persisting for at least 5 days |
Plus |
At least four of the following principle features: |
1.Extremity changes |
Erythema of palms/soles, edema of hands/feet, periungual peeling of fingers, toes in weeks 2–3 |
2.Rash |
Polymorphous exanthema, NOT bullous/vesicular |
3.Changes in lips and oral cavity |
Erythema, cracked lips, strawberry tongue, diffuse injection of oral and pharyngeal mucosa |
4.Conjunctival injection |
Bilateral, bulbar sparing limbus, nonpurulent |
5.Cervical lymphadenopathy |
>1.5 cm in diameter, usually unilateral |
Supplemental laboratory criteria |
Hypoalbuminia |
<3.0 mg/dL |
Alanine aminotransferase (ALT) |
Elevation above reference range (varies by laboratory) |
Anemia for age |
Decreased in hemoglobin below reference range for age |
Leukocytosis |
White blood cells >15,000/mm3
|
Sterile pyuria (urinalysis) |
≥10 WBC/HPF (high-power field) |
Thrombocytosis after 7 days |
Platelets >450,000/mm3 after 7 days |