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. 2020 Feb 6;37(3):1218–1232. doi: 10.1007/s12325-020-01241-0
The benefits of using intravenous (IV) iron to correct pre-operative iron deficiency anemia (IDA) have been demonstrated in numerous randomized controlled trials and include shortening the length of hospital stay, reducing red blood cell transfusion rates and improving quality of life.
Two fast-administration, high-dose IV iron formulations are currently available in Ireland: ferric carboxymaltose (Ferinject® or FCM) and iron isomaltoside 1000/ferric derisomaltose (Monover® or IIM).
A resource impact model was used to evaluate resource utilization and pre-operative IDA treatment costs in Ireland based on a combination of real-world data from an infusion clinic at Cork University Hospital, previously published models of IDA treatment, and the posological characteristics of modern IV iron formulations, including FCM and IIM.
Based on clinic throughput modeling using data from an existing IV iron clinic in Ireland, and the posological characteristics of two IV iron formulations as specified in the summaries of product characteristics, IIM was shown to result in substantially higher patient throughput than other IV iron formulations.