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. 2020 Mar 23;16(4):43. doi: 10.1007/s11306-020-01667-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Median metabolite concentrations by metabolite group and time point. Values represent the median (95% range) of the sum of the individual metabolite concentrations in each of the metabolite groups, by time point. Sums only include metabolites with data at all time points, and therefore do not include concentrations of lyso.PC.a.C20.2, PC.aa.C32.3, PC.aa.C34.5, PC.aa.C36.0, PC.aa.C38.2, PC.aa.C40.3, PC.ae.C34.4, SM.a.C30.1, SM.a.C35.0, SM.a.C37.1, SM.a.C38.3, SM.a.C39.2, SM.a.C40.5, SM.a.C42.4, SM.a.C44.6, SM.e.C36.2, and SM.e.C40.5. SM includes SM.a plus one SM.e. AA amino acids, PC.aa diacyl-phosphatidylcholines, PC.ae acyl-alkyl-phosphatidylcholines, Lyso.PC.a acyl-lysophosphatidylcholines, Lyso.PC.e alkyl-lysophosphatidylcholines, SM sphingomyelines, NEFA non-esterified fatty acids, Free Carn free carnitine, Carn.a acyl-carnitines