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. 2020 Mar 17;10:105. doi: 10.3389/fcimb.2020.00105

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Copyright © 2020 Fernández de Ullivarri, Arbulu, Garcia-Gutierrez and Cotter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The antifungal peptide development process. As with any drugs, AFPs must undergo several stages of development to reach clinical use. When the candidate molecule shows promise as a therapeutic (Discovery) it must be characterized (In vitro characterization). In order to facilitate this, sufficient amounts of the peptide must be available (Production). Finally, the molecule will be subjected to formulation processes and preclinical tests before going into clinical trials and receive approval (Development and market).