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Short-term active protective immunity against DENV3 challenge (n = 8). Mice were challenged with DENV3 at the ninth week after the immunization and monitored daily for 27 days. (A) Pathological symptoms recorded as the mean clinical sign scores. (B) Percentage of body weight from day 0. (C) Survival rate shown as the percentage of survivors. Results are representative of three independent experiments. **p < 0.01; ***p < 0.001.
