Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 17;10:87. doi: 10.3389/fcimb.2020.00087

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Feng, Zheng, Wang, Gao, Fan, Sheng, Zhou, Chen and An.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Long-term NAb response and active protective immunity against DENV3 challenge at the 12th month after the immunization (n = 6). (A) Endpoint titers of DENV3-specific NAbs in sera were detected by PRNT₅₀ and recorded as GMT ± SD. The L.O.D. depicted as a dotted line represents the limit of detection of the assay. (B–D) Mice were challenged with DENV3 and monitored daily for 27 days. (B) Pathological symptoms recorded as the mean clinical sign scores. (C) Percentage of body weight from day 0. (D) Survival rate shown as the percentage of survivors. **p < 0.01; ***p < 0.001.