Table 2.

The adipokine production by adipocytes differentiated from ADSCs in media with different deuterium content (Control – differentiation medium was made on the base of milliQ water; ddw – differentiation medium was made on the base of deuterium-depleted water; D₂O – differentiation medium was made on the base of deuterated water).

№	Adipokines,	control, M ± SD (1)	ddw, M ± SD (2)	D20, M ± SD (3)
1	Leptin	57,02 ± 12,77	142,56 ± 23,07	17,26 ± 8,53
			p1–2 = 0,0021	p1–3 = 0,0003
				p2–3 = 0,0001
2	Adiponectin	67,19 ± 15,53	175,12 ± 30,90	33,17 ± 13,77
			p1–2 = 0,0048	p1–3 = 0,0261
				p2–3 = 0,0008
3	Adipsin	63,66 ± 16,20	35,36 ± 3,76	91,52 ± 16,24
			p1–2 = 0,0228	p1–3 = 0,0659
				p2–3 = 0,0011
4	Vaspin	39,29 ± 14,07	16,83 ± 2,86	0,92 ± 0,38
			p1–2 = 0,0293	p1–3 = 0,0034
				p2–3 = 0,0004
5	Chemerin	77,82 ± 11,80	20,12 ± 3,59	16,99 ± 7,28
			p1–2 = 0,0005	p1–3 = 0,0003
				p2–3 = 0,5052
6	TNF-α	17,89 ± 0,16	12,27 ± 0,77	0,87 ± 0,39
			p1–2 = 0,0001	p1–3 = 0,0001
				p2–3 = 0,0001
7	IL-6	28,14 ± 5,97	106,60 ± 40,41	11,66 ± 1,98
			p1–2 = 0,0138	p1–3 = 0,0068
				p2–3 = 0,0008
8	IL-8	46,26 ± 10,89	21,29 ± 6,34	73,49 ± 7,97
			p1–2 = 0,0065	p1–3 = 0,0093
				p2–3 = 0,0002
9	IL-10	11,15 ± 1,69	5,63 ± 1,78	25,59 ± 8,41
			p1–2 = 0,0191	p1–3 = 0,0135
				p2–3 = 0,0059
10	MCP-1	30,68 ± 6,77	1,76 ± 0,92	5,51 ± 2,31
			p1–2 = 0,0024	p1–3 = 0,0008
				p2–3 = 0,0203
11	IP-10	8,12 ± 2,61	1,78 ± 1,51	3,24 ± 2,16
			p1–2 = 0,0446	p1–3 = 0,0348
				p2–3 = 0,7377